To make mod installation easy, download Nexus Mod Manager (NMM). With NMM you can download mods with a click of a button from the Nexus Mods website, which makes installing and uninstalling mods very easy. For those new to modding, I recommend using Nexus Mod Manager.
First of all, you will need to download Fallout 4 Script Extender (F4SE).
After installing F4SE, you will start Fallout 4 by using f4se_loader.exe. Again, you will NOT start Fallout 4 by launching it from Steam. If you do not start Fallout 4 with the f4se_loader.exe, F4SE features will not be loaded correctly.
Please see the 2 minute video to the right that shows you how to properly install F4SE.
This is a Fallout 4 program I developed. The program allows you to change quite a few common settings that many people usually do to their ini files (Fallout4.ini and Fallout4Prefs.ini). You can change your FOV settings, disable motion blur, disable mouse acceleration, disable depth of field, and more.
Description of LOOT from the author - WrinklyNinja:
Setting the right load order for your mods is a crucial step to enjoying a stable modded game. The Load Order Optimisation Tool (LOOT) can help with that, by providing automated load order sorting that's simple to use and fully customisable.
While sorting, LOOT checks for load order errors (such as incompatibilities and missing requirements) and notifies you of any issues that it detects. It also provides thousands of plugin-specific messages, such as usage notes and bug warnings, to help keep your game healthy.
Run LOOT to organize the load order of your mods so that your game won't crash. You should run LOOT after installing any mod. Also, make sure to read the mod descriptions to see if that particular mod should be loaded last/after another certain mod, because LOOT is not perfect.
If you've heard about BOSS in the past (for oldschool load order sorting for like Oblivion), LOOT is the superior successor to BOSS.